2011年9月27日 星期二

Postdoctoral opportunity

NIH-funded Postdoctoral Position to learn more about the functions of cuticular proteins in Anopheles gambiae at the University of Georgia, Athens, Georgia USA.

Structural cuticular proteins (CPs) constitute almost 2% of the protein coding genes of Anopheles.  We already know the temporal expression patterns of all and the spatial expression patterns of many.  CPs have been implicated in insecticide and desiccation resistance as well as differences in incipient species.  We are now probing more deeply into how individual CPs contribute to the structure and function of cuticle.

Research is focused on attempting to reduce CP gene expression with RNAi, localizing individual cuticular proteins within the cuticle of specific structures, learning whether CP genes are active in adults and whether expression can be induced.  We are also planning to learn if/how the structure of CPs is related to chitin and intermolecular binding.

Excellent opportunity for someone with strong molecular skills, creativity and common sense to work on challenging problems in a small research group.

Two former postdocs came from a Bombyx background and returned to moths after making significant contributions to the Anopheles project.

For more information contact Judy Willis:  jhwillis@uga.edu